This is a 2.4 GHz wireless keyboard & Mouse. It will work properly if the nano USB receiver is plugged in AFTER OS4.1 boots, but if it is plugged in during boot up, the mouse will not work but the keyboard does work.
This is terrific, inexpensive PCI card which adds a total of seven USB2 ports to your older AmigaOne computer. Recommended for AmigaOne SE and XE models as well as Pegasos II-based systems.